Newsletter excerpts: 10 Studies on Chronic Pain Conditions--July 2022

Posted by: Michelle Burns
Date Posted: July 20, 2022

Here is some of the information I recently shared in the July newsletter. Each newsletter has a specific focus.  This newsletter is focused on chronic pain conditions. If you would be interested in receiving my newsletters, which include links to the studies as well as special offers and sales coupons, please head over to my contact page and sign up.


  1. Aerobic exercise for pain intensity
  2. Effect of Curcumin on Neuroinflammation
  3. Melatonin moderates chronic pain, sleep architecture and immunometabolism
  4. Ketamine for treatment of chronic pain
  5. Effectiveness of MFR on pain, sleep and quality of life
  6. Effects of Vitamin D on pain severity
  7. Reflexology for Fibromyalgia
  8. Effect of acupuncture for fibromyalgia
  9. Effectiveness of reformer pilates for fibromyalgia
  10.  Infrared radiation for chronic pain


1. An article titled Aerobic Physical Exercise for Pain Intensity, Aerobic Capacity, and Quality of Life in Patients with Chronic Pain: A Systematic Review and Meta-Analysis published in Journal of Physical Activity and Health in Aug 2021 concludes: Aerobic exercise is a nonpharmacological therapeutic option for treatment (of chronic pain). Also, aerobic capacity and endurance improved when this type of exercise was prescribed, thus resulting in a substantial improvement in the quality of life of people suffering from chronic pain.

2.  An article titled Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain, published in Pharmaceuticals  in August 2021, reviews and details the role of curcumin in microglia and astrocytes both in vitro and in vivo and how it improved pain.

3. An article titled Melatonin Moderates the Triangle of Chronic Pain, Sleep Architecture and Immunometabolic Traffic, published in Biomedicines in Aug 2021, details and reviews current literature relevant for the shared pathways of sleep, pain, and immunometabolism and elaborates the impact of melatonin on the crossroad of sleep, chronic pain, and immunometabolism.

4. A review titled Ketamine for the Treatment of Chronic Pain: A Comprehensive Review published in Health Psychology Research in 2021 highlights the use of ketamine for: neuropathic pain, fibromyalgia, complex regional pain syndrome, phantom limb pain, cancer pain, and post-thoracotomy pain syndrome.

5. A study titled Effectiveness of myofascial release on pain, sleep, and quality of life in patients with fibromyalgia syndrome: A systematic review published in Complementary Therapies in Clinical Practice in November 2021 concludes: moderate evidence for the effect of therapist-administered and self-myofascial release in improving pain, sleep subscales, and quality of life against sam and no treatment, respectively, in fibromyalgia syndrome patients

6. A study, titled  Effects of Vitamin D on Pain severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia published in Medicine International Istanbul Hastanesi in 2021 concludes: Vitamin D deficiency may be a factor associated with symptom severity, sleep and wakefulness problems, and physical function in FMS. Therefore, serum 25OHD status should be evaluated in patients with FMS and its importance in treatment management should not be ignored.

7. A study titled The effect of Reflexology in patients with Fibromyalgia, published in Signa Vitae (Anesthesiology Department, Pain and Palliative Care Center Aretaeion Hospital, University of Athens, Athens Greece) in Feb 2020 concludes:  Reflexology may be beneficial as add-on treatment in patients with Fibromyalgia who are unable to receive the recommended dosages of their medication (pregabalin).

8. A study titled The effects of acupuncture in fibromyalgia: integrative review published in April 2020 in BrJP Sao Paulo concludes: studies suggest that acupuncture is effective for the treatment of pain in patients with fibromyalgia, with improved quality of life and positive interference in sleep.

9.  A study titled Investigation of effectiveness of reformer pilates in individuals with fibromyalgia: a randomized controlled trial published in Reumatlogía Clínical in Feb 2022 concludes: reformer pilates exercises had positive effects on clinical status and muscle strength while home mat pilates exercises had positive effects on the number of painful regions, clinical status, biopsychosocial status and physical component quality of life.

10.  An article titled Infrared Radiation in the Management of Musculoskeletal Conditions and Chronic Pain: A Systematic Review published in European Journal of Investigation Health, Psychology and Education in Mar 2022 concludes: based on findings of our review, we noted a decrease in pain levels, decrease in Fibromyalgia Impact Questionnaire scores.


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